Peak and trough levels are methods used to establish the effectiveness of a drug.
Peak:
- Highest drug level after distribution
- Drawn after the last dose of drug, usually one hour.
- Commonly obtained with use of aminoglycosides
- Used to change dose
Trough:
- Lowest drug level that is needed to reach therapeutic range
- Drawn before the next dose of drug is given.
- Commonly obtained with use of vancomycin
- Used to change frequency
Subscribe to:
Post Comments (Atom)
No comments:
Post a Comment